Product Description
Benzethonium chloride is a next-generation quaternary ammonium-type antimicrobial agent widely adopted in the daily-use chemical and cosmetic industries. Thanks to its outstanding bactericidal and antibacterial capabilities, it functions as a vital functional component in numerous hygiene and personal-care products.
Moreover, it boasts substantial applications within the medical and healthcare fields as an effective antibacterial ingredient. For instance, it is commonly used in Western countries as an antimicrobial additive in eye drops and injectable preparations.
Additionally, benzethonium chloride acts as an essential intermediate for the manufacture of heparin sodium, underscoring its pivotal position in pharmaceutical production.
Chemical Properties
| Melting point | 162-164 °C (lit.) |
| Boiling point | 162℃[at 101 325 Pa] |
| Density | 0.998 g/mL at 20 °C |
| Vapor pressure | < 0.001 hPa @ 2°C |
| Refractive index | 1.5650 (estimate) |
| Storage temp. | 2-8°C |
| Solubility | H2O: 0.1 M at 20 °C, clear, colorless |
| Form | Liquid |
| Color | White |
| PH | 5.5-7.5 (25℃, 0.1M in H2O) |
| Odor | Odorless |
| PH Range | 5.5 - 7.5 |
| Water Solubility | 1-5 g/100 mL at 18 ºC |
| Sensitive | Hygroscopic |
| Merck | 141074 |
| BRN | 3898548 |
| Stability | Stability Stable, but hygroscopic. Incompatible with strong oxidizing agents, soap, anionic detergents, nitrates, acids. Light sensitive. |
| LogP | 1.08 at 20℃ |
| CAS DataBase Reference | 121-54-0(CAS DataBase Reference) |
| EPA Substance Registry System | Benzethonium chloride (121-54-0) |
Safety Information
| Hazard Codes | Xn,N,C |
| Risk Statements | 22-37/38-41-36-36/37/38-20/21/22-50/53-34-52/53 |
| Safety Statements | 26-36/39-24/25-36/37/39-61-45 |
| RIDADR | UN1759 |
| WGK Germany | 2 |
| RTECS | BO7175000 |
| F | 8 |
| TSCA | Yes |
| HazardClass | 8 |
| PackingGroup | III |
| HS Code | 29239000 |
| Hazardous Substances Data | 121-54-0(Hazardous Substances Data) |
| Toxicity | LD50 i.v. in mice: 29.5 mg/kg (Weiss) |
Product Application
Benzethonium chloride maintains a steady and extensive market position throughout the pharmaceutical, daily-use chemical and cosmetic industries.
In the heparin sodium field alone, its annual demand surpasses 200 tons. It is mainly applied in the purification of heparin sodium, as well as the production of low-molecular-weight heparin sodium and enoxaparin.
Within the daily-use chemical sector, disinfecting wipes widely adopt benzethonium chloride as an active bactericidal component, with annual consumption amounting to dozens of tons. Meanwhile, demand in the broader personal care and hygiene market is growing rapidly, and total consumption is projected to keep increasing.
This ingredient is also highly popular for cosmetic formulation and environmental disinfection purposes, featuring great promotion potential, a wide application range and promising market prospects.
