Dimethyl Sulfoxide

1.Versatile Solvent:Dimethyl sulfoxide (DMSO) is an effective polar aprotic solvent capable of dissolving both polar and nonpolar compounds, making it highly versatile for a wide range of applications.

2.High Miscibility:It is miscible with a broad range of organic solvents and with water, enhancing its compatibility in different environments and processes.

3.Efficient in Various Applications:Suitable for industrial, chemical, and pharmaceutical uses.

4.Established History:First synthesized in 1866, DMSO has a long history of use across various chemical and industrial fields, demonstrating its reliability and effectiveness over time.

Product Details

Dimethyl sulfoxide is an organosulfur compound first synthesized in 1866 by Alexander Zaytsev in the Russian Empire. This colorless liquid is an important polar aprotic solvent, capable of dissolving both polar and nonpolar substances. It is miscible with a variety of organic solvents and with water.

Dimethyl Sulfoxide

Chemical Properties

Melting point18.4 °C
Boiling point189°C(lit.)
density1.100 g/mL at 20°C
vapor density2.7 (vs air)
vapor pressure0.42 mm Hg ( 20 °C)
refractive indexn20/D 1.479(lit.)
FEMA3875 | METHYLSULFINYLMETHANE
Fp192 °F
storage temp.Store at +5°C to +30°C.
solubilityH2O: miscible (completely)
pka35(at 25℃)
formliquid (temperature dependent)
colorclear colorless
Relative polarity0.444
OdorMild garlic odor
Odor Typealliaceous
biological sourcesynthetic
explosive limit1.8-63.0%(V)
Water SolubilitySoluble in water, methanol, acetone, ether, benzene, chloroform.
FreezingPoint18.4℃
SensitiveHygroscopic
λmaxλ: 285 nm Amax: ≤0.20
λ: 295 nm Amax: ≤0.20
JECFA Number507
Merck14,3259
BRN506008
Dielectric constant41.9(55℃)
StabilityStable. Incompatible with a very wide range of materials, including acid chlorides, strong acids, strong oxidizing agents, strong reducing agents, phosphorus halides, moisture, copper wool + trichloroacetic acid. Reacts violently with a number of materials - consult a full data sheet before use. Hygroscopic.
InChIKeyIAZDPXIOMUYVGZ-UHFFFAOYSA-N
LogP-1.35
Surface tension42.179mN/m at 298.15K
CAS DataBase Reference67-68-5(CAS DataBase Reference)
NIST Chemistry ReferenceDimethyl sulfoxide(67-68-5)
EPA Substance Registry SystemDimethyl sulfoxide (67-68-5)
Absorptionpasses test

Product Application

DMSO is a polar aprotic solvent used in chemical reactions, polymerase chain reactions (PCR), and as a cryoprotectant for vitrification in the preservation of cells, tissues, and organs. It helps prevent mechanical damage to cells caused by ice crystal formation during freezing. DMSO is commonly employed in the storage of primary, subcultured, and recombinant heteroploid and hybridoma cell lines, as well as embryonic stem cells (ESC) and hematopoietic stem cells. In these applications, it is often combined with BSA or fetal bovine serum (FBS).

Dimethyl Sulfoxide

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