Product Details
1-Propanethiol is a sulfur-containing organic compound with the formula C₃H₈S. At room temperature, it appears as a clear, colorless liquid with a strong odor. As an important chemical intermediate, 1-propanethiol is widely used in the pharmaceutical, pesticide, and fine chemical industries. Its molecular structure contains a thiol (-SH) group, which provides strong nucleophilicity, making it a valuable raw material for synthesizing sulfur-containing drugs such as anti-ulcer medications and antibiotics. Additionally, it plays a key role in the production of rubber and fragrances.
Product Parameter
| Melting point | -113 °C |
| Boiling point | 67-68 °C(lit.) |
| Density | 0.841 g/mL at 25 °C(lit.) |
| Vapor density | 2.54 (vs air) |
| Vapor pressure | 122 mm Hg ( 20 °C) |
| Refractive index | n20/D 1.437(lit.) |
| FEMA | 3521 | PROPANETHIOL |
| Fp | −5 °F |
| Storage temp | Store below +30°C. |
| Solubility | 1.9g/l |
| Pka | pK1:10.86 (25°C) |
| Form | Liquid |
| Color | Colorless |
| Odor | At 0.10 % in propylene glycol. cabbage natural gas sweet onion |
| Odor Threshold | 0.000013ppm |
| Odor Type | Alliaceous |
| Biological source | Synthetic |
| Water Solubility | Immiscible |
Product Application
Key Drug Intermediates
1-Propanethiol serves as an essential synthetic raw material for proton pump inhibitor anti-ulcer drugs such as omeprazole and lansoprazole, where its thiol group plays a crucial role in binding with the drug molecular framework.
Innovative Biomedical Applications
It is used as a protein drug modifier to enable site-specific modifications via thiol-disulfide bond exchange, and is also employed in designing the active structures of new fungicides to broaden their antifungal spectrum.
High-Efficiency Pesticide Synthesis
1-Propanethiol acts as a vital thio-precursor for organophosphorus insecticides like propylthiophos, directly influencing their effectiveness.
Advanced Polymer Materials
As a specialized rubber vulcanization accelerator, 1-propanethiol significantly enhances product performance and is used in the synthesis of functional polymers that impart unique properties to materials.
Innovations in Electronic Materials
It is an important precursor for semiconductor thin-film vapor deposition, a doping modifier for new conductive polymers, and a core synthetic raw material for photoelectric conversion materials.
Breakthroughs in New Energy Technologies
1-Propanethiol serves as a key electrolyte additive in lithium-sulfur batteries to address polysulfide shuttling issues, and functions as a catalyst carrier modifier in fuel cells to enhance catalytic efficiency.
