Products Description
1-Phenoxy-2-propanol is an important synthetic intermediate used in the production of acyl arylthiocarbamates, which function as non-nucleoside reverse transcriptase inhibitors. It appears as a transparent, viscous liquid with a boiling point of 243 °C. Its boiling range is 125–135 °C at 2.8 kPa and 104–114 °C at 1.3 kPa. The relative density is 1.463, the refractive index ranges from 1.5243 to 1.5245, and the flash point is above 110 °C.
Chemical Properties
| Melting point | 11 °C |
| Boiling point | 243 °C (lit.) |
| Density | 1.064 g/mL at 20 °C (lit.) |
| Vapor pressure | 1Pa at 20℃ |
| Refractive index | n20/D 1.523(lit.) |
| Fp | >230°F |
| Storage temp | Refrigerator |
| Solubility | water: soluble15.1g/L at 20°C |
| Pka | 14.43±0.20(Predicted) |
| Form | Oil |
| Color | Clear Colourless |
| Specific Gravity | 1.051 |
| Water Solubility | 15.1g/L at 20℃ |
| BRN | 1941356 |
| Stability | Stable. Flammable. Incompatible with strong oxidizing agents. |
| LogP | 1.41 at 24.1℃ |
| CAS DataBase Reference | 770-35-4(CAS DataBase Reference) |
| NIST Chemistry Reference | 1-Phenoxy-2-propanol(770-35-4) |
| EPA Substance Registry System | 1-Phenoxy-2-propanol (770-35-4) |
Safety Information
| Hazard Codes | Xi |
| Risk Statements | 36 |
| Safety Statements | 23-26 |
| WGK Germany | 1 |
| RTECS | UB8886500 |
| TSCA | Yes |
| HS Code | 29094990 |
| Hazardous Substances Data | 770-35-4(Hazardous Substances Data) |
| Toxicity | LD50 orl-rat: 2830 mg/kg NTIS** OTS0539745 |
| Storage temp | Refrigerator |
| Solubility | water: soluble15.1g/L at 20°C |
