1,2-O-Isopropylidene-Alpha-DXylofuranose

Core Chiral Building Block: Acts as a vital chiral intermediate for the synthesis of atorvastatin side-chains and other pharmaceutical molecules.

High Synthetic Utility: Can be transformed into 3-deoxy-1,2-O-isopropylidene-D-xylofuranose, allowing further assembly of complex molecular structures.

Facilitates Pharmaceutical Development: Performs an essential function in manufacturing numerous drug intermediates, increasing its importance in pharmaceutical research.

Wide-Ranging Synthetic Compatibility: Suitable for multiple organic synthetic routes, supporting the development of various bioactive compounds.

Description of 1,2-O-Isopropylidene-α-D-Xylofuranose (CAS No. 20031-21-4)

1,2-O-Isopropylidene-α-D-xylofuranose can act as a starting material for producing 3-deoxy-1,2-O-isopropylidene-D-xylofuranose. This product functions as a chiral building block for constructing the pharmacologically active side chain of atorvastatin, and also serves a vital role in the synthesis of many other pharmaceutical intermediates.

1,2-O-Isopropylidene-α-D-Xylofuranose (CAS No. 20031-21-4)

1,2-O-Isopropylidene-Alpha-D-Xylofuranose Chemical Properties

Melting point 69-71 °C(lit.)
Boiling point 112-114 °C0.06 mm Hg(lit.)
Alpha -19.2 º (C=1 IN H2O)
Density 1.2422 (rough estimate)
Refractive index -19 ° (C=1, H2O)
Storage tempKeep in dark place,Sealed in dry,Room Temperature
Solubility Methanol (Slightly), Water (Slightly)
Pka13.23±0.60(Predicted)
Form Waxy Solid or Coarse Crystals and Chunks
Color White to Off-white
Optical activity[α]25/D 19.2°, c = 1 in H2O
BRN 81520
InChIKeyJAUQZVBVVJJRKM-VZFHVOOUSA-N
CAS DataBase Reference20031-21-4(CAS DataBase Reference)
EPA Substance Registry System.alpha.-D-Xylofuranose, 1,2-O-(1-methylethylidene)- (20031-21-4)
Safety Statements 22-24/25
WGK Germany 3
10
HS Code 29321900
1,2-O-Isopropylidene-Alpha-D-Xylofuranose

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